Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Ephedrine infusion: Group E, will receive an infusion of Epinephrine at a rate of 0.03 mcg/kg/min from the time of administration of spinal till the end of surgery in a 50 ml syringe pu
Sponsors
Office of the Principal, Midnapore Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients giving valid consent 2. All ASA criteria I and II 3. Elective LSCS 4. Patient between 18 to 35 years of age 5. Term singleton pregnancy
Exclusion criteria
Exclusion criteria: a. Patient’s refusal. b. Patients with medical complications like diabetes, CVA, cardio respiratory disease, hepatic, renal or endocrine disease. c. Obstetric complications like breech presentation, twin pregnancy, placenta previa, placental abruption, pregnancy induced hypertension (PIH). d. Patients with autonomic neuropathy, spinal deformity or coagulation abnormality. e. Patients with neonatal compromise like fetal bradycardia meconium stained liquor, IUGR. f. Failed spinal ,repeat spinal, patchy spinal, Conversion to general anesthesia at any moment of surgery is excluded from study. g. Patient with history of allergy to study drugs h. Height 180 cm i. Weight 100kg.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To monitor and record hemodynamic parameters like Heart rate, SBP,DBP,MAP at specific time intervals and compare between studies. 2. To record the incidence of bradycardia and hypotension episodes in both groups.Timepoint: baseline (0 min), 2 min, 4 min, 6 min, 8 min, 10 min, 15 min, 20 min, 25 min, 30 min, 35 min, 40 min, 45 min, 50 min, 55 min, 60 min | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse effects like tachycardia, hypertension, intra operative nausea vomiting and complications if any.Timepoint: baseline (0 min), 2 min, 4 min, 6 min, 8 min, 10 min, 15 min, 20 min, 25 min, 30 min, 35 min, 40 min, 45 min, 50 min, 55 min, 60 min;To compare the neonatal outcome between the two groups by measuring APGAR scores at one minute and five minute , umbilical cord blood gas analysis. Timepoint: 1 min, 5 min after baby delivery | — |
Countries
India
Contacts
Public ContactDr Bijoy Kumar Bandyopadhyay
Midnapore Medical College and Hospital
Outcome results
None listed