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Comparison of the Histological Response of the Human Dental Pulp tissue to Cryotherapy and Sodium Hypochlorite When Used for Control of Bleeding During Vital Pulp Therapy.

Response of Dental Pulp to Cryotherapy When Used as a Haemostatic Agent During Pulpotomy – A Histomorphologic Study - Not Applicable

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/060315
Enrollment
50
Registered
2023-11-29
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K043- Abnormal hard tissue formation inpulp

Interventions

Intervention1: Cryotherapy: Young orthodontic patients requiring premolar teeth extraction will be recruited in the study to evaluate and compare the histological response of healthy human dental pulp

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Young Patients with premolar teeth indicated for extraction due to orthodontic reasons. 2. Only sound and non-carious teeth will be included in the study.

Exclusion criteria

Exclusion criteria: 1. Teeth with dental caries, cracks, cusp fractures, and poor periodontal health. 2. Teeth not able to be isolated with rubber dam. 3. Patients with systemic conditions which could compromise the healing. 4. Patients not willing to participate in the study.

Design outcomes

Primary

MeasureTime frame
Calcified barrier morphology, Inflammation intensity, tissue response to materialTimepoint: At baseline, and at 3 months after tooth extraction for histological processing

Secondary

MeasureTime frame
Presence of dentin chips, tubules in calcific barrier, bacterial penetration, odontoblastic cell layer patterns.Timepoint: At baseline, & at 3 months

Countries

India

Contacts

Public ContactDr Sidhartha Sharma

AIIMS, New Delhi

sid.aiims@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026