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To evaluate the correlation between non-invasive (NIRS and ONSD) and invasive (ICP catheter) techniques of ICP measurements in adults with traumatic brain injury- A prospective observational study.

To evaluate the correlation between non-invasive (NIRS and ONSD) and invasive (ICP catheter) techniques of ICP measurements in adults with traumatic brain injury- A prospective observational study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/11/060200
Enrollment
30
Registered
2023-11-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G939- Disorder of brain, unspecified

Interventions

None listed

Sponsors

AIIMS, New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult (18 to 60 years), both sexes, 2. Admitted to Neurointensive Care Unit following traumatic brain injury and undergoing invasive ICP monitoring.

Exclusion criteria

Exclusion criteria: 1. Patients who have undergone decompressive craniectomy 2. Orbital trauma 3. Orbital tumor 4. History of glaucoma 5. Traumatic lesions on forehead 6. Frontal hematoma 7. Patient with low SpO 2 (< 95%) or PF ratio < 300.

Design outcomes

Primary

MeasureTime frame
To find a correlation between Non-invasive [near infrared spectrometry (NIRS) values & optic nerve sheath diameter (ONSD) values] and Invasive (intracranial ICP catheter values) techniques of ICP measurements in adult patients with traumatic brain injury.Timepoint: To find a correlation between Non-invasive [near infrared spectrometry (NIRS) values & optic nerve sheath diameter (ONSD) values] and Invasive (intracranial ICP catheter values) techniques of ICP measurements in adult patients with traumatic brain injury.—

Secondary

MeasureTime frame
1 To compare the two non-invasive techniques of ICP measurement (ONSD & NIRS) in predicting raised ICP (>22 mmHg) in adults with traumatic brain injury. 2 To establish the cut-off value for ONSD & NIRS measurements in predicting raised ICP (>22 mmHg) in adults with traumatic brain injury.Timepoint: Three clusters of measurements would be taken each day (T1, T2, T3), at least 3 hours apart from each other for 48 hours after ICP insertion. Three individual measurements of the optic nerve diameter will be obtained on each eye (rt & left), at each time point & the average of the three values will be recorded for the individual eye. Each blinded ONSD measurement will be paired with simultaneous measurement of NIRS readings (on right and left side) and invasive ICP readings.—

Countries

India

Contacts

Public ContactDr Arvind Chaturvedi

AIIMS, New Delhi

c.arvind61@yahoo.in9871045824

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026