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Study comparing two techniques of reducing vomiting after operation for removal of gall bladder by micro surgery where one technique is using a drug only and the other technique is using both drug and saline

DEXAMETHASONE VERSUS DEXAMETHASONE PLUS INTRAOPERATIVE INTRAVENOUS RINGER LACTATE (30ML/KG) INFUSION TO PREVENT POSTOPERATIVE VOMITING IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY;RANDOMISED, DOUBLE BLINDED STUDY - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/060178
Enrollment
100
Registered
2023-11-23
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Receive IV dexamethasone 8mg IV just before induction of general anaesthesia, will receive 15ml/kg body weight of ringer lactate preoperatively: 50 Patients Posted For Cholecystectomy W

Sponsors

Office of the Principal Midnapore Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 Posted for elective laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Severe Cardiopulmonary disease Hepatic and Renal Failure Neurologic disorder Endocrine disorder Not given Consent Psychiatric Problem Allergy to dexamethasone

Design outcomes

Primary

MeasureTime frame
To study and know about the efficacy of Dexamethasone plus intraoperative fluid load of 30ml/kg in preventing post operative nausea and vomiting when compared with Dexamethasone aloneTimepoint: 2hour, 4 hour, 6 hour, 12 hour, 18 hour, 24 hour after completion of surgery

Secondary

MeasureTime frame
1. To compare the requirement of rescue antiemetic between two groups 2. To compare the requirement of rescue analgesic during the first 24hr. 3. To compare the hemodynamic changes between two groups in intra operative & postoperative period. 4. To study the side effects if any attributable to drugs & infusion of liberal fluid. Timepoint: 2HR,4HR,6HR,12HR,18HR,24HR

Countries

India

Contacts

Public ContactDr Arun Kumar Mandi

Midnapore Medical College and Hospital

bjoybnrjee@gmail.com9332132242

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026