Health Condition 1: F102- Alcohol dependence
Conditions
Interventions
Intervention1: nil: nil
Control Intervention1: nil: nil
Sponsors
Mota Prachi Himansu Anila
Eligibility
Inclusion criteria
Inclusion criteria: Group 1 (ADS + ACE) 1. Individuals diagnosed with ADS 2. ADS for minimum 5 years based on ICD-11 Criteria (abstinent for at least 1 week- CIWA score less than 9) 3. Individuals with a frequency score of at least 1 on ACE-IQ 4. Males aged 18- 50 years 5. Abstinence of less than 1 year 6. At least 5 years of formal education (5th standard reading level) and ability to read, write and speak in English or Kannada Group 2 (ACE) 1. Individuals without ADS. 2. Individuals with a frequency score of at least 1on the ACE-IQ 3. Matched group (based of age and education) of males aged 18- 50 years 4. At least 5 years of formal education (5th standard reading level) and ability to read, write and speak in English or Kannada Group 3 (ADS) 1. Individuals diagnosed with ADS 2. ADS for minimum 5 years based on ICD-11 Criteria (abstinent for at least 1 week- CIWA score less than 9) 3. Individuals with a frequency score of 0 on ACE-IQ. 4. Matched group (based of age and education) of males aged 18- 50 years 5. Abstinence of less than 1 year 6. At least 5 years of formal education (5th standard reading level) and ability to read, write and speak in English or Kannada
Exclusion criteria
Exclusion criteria: Group 1 (ADS + ACE) 1. Other substance disorders (except nicotine) 2. Major psychiatric disorders (moderate to severe mood disorders, psychotic disorders, and anxiety disorders) 3. Individuals with severe cognitive deficits, for instance, individuals with Korsakoff’s syndrome, which may hinder the quality and accuracy of data collection. 4. Individuals with major neurological conditions including traumatic brain injury, road traffic accidents, epilepsy. 5. Other major medical comorbidities which may affect cognitive functioning. Group 2 (ACE) 1. Any Disorders due to Substance Use 2. Other major psychiatric disorders (moderate to severe mood disorders, psychotic disorders, and anxiety disorders) 3. Individuals with severe cognitive deficits, for instance, individuals with dementia, which may hinder the quality and accuracy of data collection. 4. Individuals with major neurological conditions including traumatic brain injury, road traffic accidents, epilepsy. 5. Other major medical comorbidities which may affect cognitive functioning. Group 3 (ADS) 1. Individuals with a frequency score of 1 or more on ACE-IQ. 2. Other substance disorders (except nicotine) 3. Major psychiatric disorders (moderate to severe mood disorders, psychotic disorders, and anxiety disorders) 4. Individuals with severe cognitive deficits, for instance, individuals with Korsakoff’s syndrome, which may hinder the quality and accuracy of data collection. 5. Individuals with major neurological conditions including traumatic brain injury, road traffic accidents, epilepsy. 6. Other major medical comorbidities which may affect cognitive functioning.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Cognitive Control a. Working Memory: Score on Verbal N2-Back Test (hits, omission, commission, error), Digit Span (forward, backward, total) and Spatial Span (forward, backward, total) b. Behavior-Inhibition & Distractor Interference Control: Go/No Go Task (mean accuracy, mean error, response time) 2.Visual Learning & Memory: Scores on Family Pictures Test (Recall 1 & 2, Percent Retention) 3.Verbal Learning & Memory: Scores on Rey’s AVLT (immediate & delayed recall, recognition). Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Nil | — |
Countries
India
Contacts
Public ContactDiti Kohli
MCHP, MAHE
Outcome results
None listed