Health Condition 1: S069- Unspecified intracranial injury
Conditions
Interventions
Intervention1: Leveteracetam: Antiepileptic drug,
500mg BD,via intravenous route, for 7 days
Control Intervention1: Phenytoin: Antiepileptic agent,
100mg TID, via intravenous route,
for 7 days
Sponsors
Hospital supplyfree of cost Sherikashmir institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1)Pts 18yrs or above 2)Pts with diagnosis of TBI 3)GCS less than 8
Exclusion criteria
Exclusion criteria: 1)Pts with history of epilepsy or seizure disorder. 2)Pt with history of hypersensitivity or allergy to phenytoin or leviteracetam. 3)Pt with history of liver or kidney disease. 4)Pts who are pregnant or breast feeding. 5)Pts who don’t give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Time to first seizure 2)total seizures during 7 days Timepoint: During 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| No. of days of icu stay. No. of days of hospital stayTimepoint: Till patient is discharged. | — |
Countries
India
Contacts
Public ContactDr Eman Aftab
Sheri-I-Kashmir Institute of Medical sciences
Outcome results
None listed