Comparison of reduction of pain by adding drugs like dexmedetomindine and nalbuphine to bupivacaine heavy in lower limb spinal surgeries

A comparative study of analgesic effect of intrathecal nalbuphine hydrochloride with 0.5% hyperbaric bupivacaine and dexmedetomidine with 0.5% hyperbaric bupivacaine in lower limb surgeries - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/060137

Enrollment

100

Registered

2023-11-22

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nalbuphine: Analgesic effect of nalbuphine when added to 0.5% bupivacaine intrathecally Control Intervention1: Dexmedetomindine: Analgesic effect of dexmedetomindine with 0.5% bupivacai

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anesthesiologists (ASA) Grade I AND II patients Patients undergoing elective lower limb surgeries

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
AnalgesiaTimepoint: 180 minutes	—

Secondary

Measure	Time frame
Motor blockadeTimepoint: 180 minutes	—

Countries

India

Contacts

Public ContactDR Nishi Jain

Peoples college of medical sciences and research centre

ph.anaesthsia@peoplesuniversity.edu.in8962241810

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026