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Comparison of respiratory problems during operation using either Propofol or Sevoflurane - Randomized trial

Respiratory adverse events after laryngeal mask airway removal in children: A randomized trial comparing Propofol to Sevoflurane - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/060122
Enrollment
100
Registered
2023-11-22
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system

Interventions

Intervention1: Sevoflurane: After laryngeal mask airway removal, the respiratory adverse events (cough, bronchospasm, laryngospasm, desaturation, stridor) between Tiva with propofol and sevoflurane wi

Sponsors

Armed Forces Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children undergoing minor surgeries of duration less than 2 hours. 2. Patient should be eligible for LMA insertion. 3. Children with American Society of Anesthesiologist (ASA) status 1 - 2.

Exclusion criteria

Exclusion criteria: 1. Pediatric patients with acute exacerbation of asthma. 2. Pediatric patients with congenital heart disease. 3. Pediatric patients with neurologic disorders. 4. Pediatric patients with full stomach. 5. Pediatric patients with hiatal heria. 6. Pediatric patients with known of predicted difficult airway. 7. Pediatric patients with facial or airway anomalies. 8. Pediatric patients with major abdominal or thoracic surgery. 9. Pediatric patients who had more than 3 attempts at LMA mask insertion.

Design outcomes

Primary

MeasureTime frame
To compare occurance of atleast one perioperative respiratory adverse event between TIVA with propofol & sevoflurane.Timepoint: Immediately till Half an hour post laryngeal mask airway removal

Secondary

MeasureTime frame
The individual adverse event following removal of LMA mask.Timepoint: Immediately till Half an hour post laryngeal mask airway removal;The severity of airway hyper reactivity using the airway hyper reactivity score of Pappas et al. Timepoint: Immediately post laryngeal mask airway removal

Countries

India

Contacts

Public ContactDr Gunjan Singh

Armed Forces Medical College

gunjanafmc@gmail.com9612112136

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026