A study to compare the efficacy of the drug dexamethasone and lidocaine when used before surgery as inhalation to prevent post operative sore throat

A study to evaluate the efficacy of nebulization with Dexamthasone and Lidocaine preoperatively on post operative sore throat(POST) - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/060109

Enrollment

135

Registered

2023-11-21

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Y838- Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

Interventions

Intervention1: Dexamethasone 8mg Lidocaine 4% Normal Saline 5ml: Two groups of patients will be nebulized via inhalational route with Dexamethasone 8mg and Lidocaine 4% (80mg) each and one with normal

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients of ASA physical status I and II, age between 18 and 60 years of either sex, undergoing elective surgeries in supine position under General Anaesthesia with endotracheal intubation lasting

Exclusion criteria

Exclusion criteria: Patients with recent sore throat( Patients with history of recent( Pregnant patients. Patients with present chronic airway disease. Anticipated difficult airway. Patients undergoing head and neck procedures. Patient refusal

Design outcomes

Primary

Measure	Time frame
The incidence of Postoperative sore throat at 4 hours post extubationTimepoint: The incidence of Postoperative sore throat at 4 hours post extubation	—

Secondary

Measure	Time frame
Incidences & severities observed at 2 4 8 12 & 24 hours post surgery on a four point scale for Any hoarseness of voiceTimepoint: 0 no hoarseness 1 mild hoarseness 2 moderate hoarseness 3 severe hoarseness	—

Countries

India

Contacts

Public ContactRahul Dayora

PT. BDS university of health sciences Rohtak

rahulprazapati@gmail.com9991540213

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026