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Sensory Stimulation by caregivers to improve consciousness in persons with severe brain injury

Caregiver-mediated Vellore intense Multimodal Sensory Stimulation (Vi-MuSt) for improving the level of consciousness in patients with severe brain injury: A Single-blind, Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/060074
Enrollment
22
Registered
2023-11-21
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S098- Other specified injuries of head

Interventions

Intervention1: Caregiver-mediated Vellore intense Multimodal Sensory Stimulation (Vi-MuSt): The patients in the intervention group will receive a 4-week, residential, interdisciplinary rehabilitation

Sponsors

Christian Medical College Vellore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with brain injury who are in Coma, Unresponsive Wakefulness Syndrome (UWS) and Minimally Conscious State (MCS), RLA stage I to III (No response, generalized response and localized response).

Exclusion criteria

Exclusion criteria: Patients with complications such as recurrent seizures, unstable vital signs will be excluded.

Design outcomes

Primary

MeasureTime frame
JFK Coma recovery scale- Revised (CRS-R), Wessex Head Injury Matrix (WHIM)Timepoint: Pre-assessment will be done in the first week after the allocation to the group and Post assessment after 4 weeks following the pre-assessment in both the groups.

Secondary

MeasureTime frame
Disability Rating Scale (DRS)Timepoint: Pre-assessment will be done in the first week after the allocation to the group and Post assessment after 4 weeks following the pre-assessment in both the groups.

Countries

India

Contacts

Public ContactJones Jeromedanypraveenraj

Christian Medical College, Vellore

jeromedany18@gmail.com9894832099

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026