Health Condition 1: C49- Malignant neoplasm of other connective and soft tissue
Conditions
Interventions
Intervention1: Radiation therapy,
Surgery: Patient will receive stereotactic body radiotherapy 30-40Gy/5#/alternate days to target site followed by surgery of primary site 4-6 weeks after completion o
Sponsors
AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: Age: >15years. Hemoglobin >9% pretreatment. Biopsy proven soft tissue sarcoma. Site: extremities, trunk, head and neck. Size Resectable and borderline resectable tumors. Informed consent. ECOG PS 0-2.
Exclusion criteria
Exclusion criteria: No histopathological proof or malignancy. Doubtful follow-up. Previous history of radiotherapy in target area. Uncontrolled co-morbid conditions e.g. hypertension, diabetes mellitus, coronary artery disease. Contraindications of CT/MRI. Deranged LFT, KFT. Recurrent disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess major wound complication rates post surgery. Pathological response rateTimepoint: Major wound complication rates post surgery are assessed within 6 months post surgery. Pathological response rate | — |
Secondary
| Measure | Time frame |
|---|---|
| radiological tumor response post radiotherapy.Timepoint: radiological tumor response is assessed one week before surgery.;to assess early and late complications post surgery.Timepoint: early and late complications are assessed at 6 weeks, 4 months, 6 months post surgery.;to assess local control and disease free survival post surgery.Timepoint: local control and disease free survival are assessed up-to 6 months post surgery. | — |
Countries
India
Contacts
Public ContactGanta Mounika
All India Institute of Medical sciences
Outcome results
None listed