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Comparision of 2 drugs( hyperbaric bupivacaine and hyperbaric ropivacaine) used in spinal anaesthesia for caeserean section in patients with pregnancy induced hypertension

Comparison of hyperbaric ropivacaine and hyperbaric bupivacaine for Spinal Anaesthesia in Pregnancy Induced Hypertension (PIH) parturients undergoing Caesarean Section - A randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/060021
Enrollment
146
Registered
2023-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Hyperbaric Ropivacaine: Injection of 0.75% Hyperbaric Ropivacaine, 1.8 ml, during spinal anaesthesia, from injection of drug until the patient is shifted to recovery room and starts amb

Sponsors

RAJESHKUMAR N
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Hypertensive disorders of pregnancy planned for elective caesarean section under Spinal Anaesthesia

Exclusion criteria

Exclusion criteria: Hypersensitivity to any of the study drugs, Patients with spinal deformity, Patients with coagulopathy, Short stature (less than 140 cms), Elderly primigravida, Precious pregnancy, Other comorbidities like Diabetes Mellitus, CAD, Congenital heart diseases, Valvular heart diseases etc.

Design outcomes

Primary

MeasureTime frame
To compare the incidence of hypotension with Inj. 0.75% Hyperbaric Ropivacaine as compared to Inj. 0.5% Hyperbaric Bupivacaine during Spinal Anaesthesia for Caesarean Section in PIHTimepoint: Untill patient is shifted to recovery room

Secondary

MeasureTime frame
1)To compare the onset and regression of sensory block up to T10 between 2 groups. 2)To compare the onset and regression of motor block between 2 groups. 3)To compare incidence of side effects between 2 groups.Timepoint: untill regression of sensory block and motor block in recovery room

Countries

India

Contacts

Public ContactDr STALIN V

Jawaharlal Institute of Postgraduate Medical Education and Research

drvstalin@gmail.com9786397762

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026