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To study the effects of remote ischemic preconditioning in cardiac patients undergoing off pump coronary artery bypass grafting procedure

Effects of remote ischemic preconditioning in patients undergoing off pump coronary artery bypass grafting procedure-A Randomised controlled study - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/060015
Enrollment
134
Registered
2023-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Interventions

Intervention1: Remote ischemic preconditioning receiving group: Standard BP cuff will be placed in right upper arm and left lower limb and inflated simultaneously to 200 mmHg for a period of 5 minutes

Sponsors

SRM Medical College Hospital and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient undergoing primary , elective OFF pump coronary bypass grafting procedure for double/triple coronary artery disease. 2.ASA 3 and 4

Exclusion criteria

Exclusion criteria: 1.Patient in cardiogenic shock 2.Cardiac arrest in current hospital admission 3. Pregnancy 4. Disease related to preoperative renal insufficiency , peripheral vascular disease , inotropic support before induction of anesthesia

Design outcomes

Primary

MeasureTime frame
Remote ischemic preconditioning will be associated with reduced perioperative concentration of cardiac troponin I in patients undergoing off pump coronary artery bypass grafting procedureTimepoint: Cardiac troponin I will be assessed at 24 hr,48hr,72hr postoperatively

Secondary

MeasureTime frame
1.Incidence of intraoperative and postoperative arrhythmia in first 72 hours. 2.Acute Kidney injury 3.Major adverse cardiac events 4.Duration of mechanical ventilation 5.Length of ICU stayTimepoint: Patients will be monitored in ICU for 72 hours postoperatively

Countries

India

Contacts

Public ContactDr Gayatri B

SRM Medical College Hospital and Research institute

gayathrii.r@gmail.com9500092905

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026