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Effectiveness of before operation inhalation of two drugs in reducing after operation sore throat following general anaesthesia with intubation

Efficacy of preoperative nebulization with Ketamine and Magnesium sulphate in reducing post operative sore throat following general anaesthesia with endotracheal intubation. A double blinded randomised control study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/060000
Enrollment
120
Registered
2023-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: PCS- Health Condition 3: O- Medical and Surgical

Interventions

Intervention1: Ketamine nebulization: Ketamine nebulization with Ketamine 50mg in 5ml normal saline.15minutes before induction of general anaesthesia to prevent postoperative sore throat Intervention2

Sponsors

S Nijalingappa Medical College and HSK hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.all consented patients of either sex. 2.aged 18-65years. 3.patient belonging to ASA physical status 1 or 2 4.patient posted for elective surgeries requiring general anaesthesia with endotracheal intubation. 5.surgeries lasting 2-3hours.

Exclusion criteria

Exclusion criteria: 1.patient belonging to ASA physical stauts grade 3 or 4 2.surgeries lasting for more than 3 hours. 3.patients with history of pre operative sore throat . 4.anticipated difficult airway. 5.head and neck surgeries. 6.surgeries requiring prone position. intubation attempts more than 2 hours.

Design outcomes

Primary

MeasureTime frame
to compare the efficacy of preoperative nebulization of ketamine & magnesium sulphate in reducing the incidence of post operative sore throat following general anaesthesis with endotracheal intubation.Timepoint: 24hours—

Secondary

MeasureTime frame
To compare postoperative sore throat with control groupTimepoint: 48hours—

Countries

India

Contacts

Public ContactDr Swetha R

SNMC and HSK hospital Bagalkot, navanagar

drbasupadara@gmail.com8762363790

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026