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Comparision of blood product and polymer solution included blood product for the treatment of jaw joint problem.

Comparison of Injectable Platelet-Rich Fibrin and Hyaluronic Acid Combination versus Injectable Platelet-Rich Fibrin Only in Internal Derangement Of Temporomandibular Joint: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/059991
Enrollment
28
Registered
2023-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M248- Other specific joint derangements,not elsewhere classified

Interventions

Intervention1: Injectable Platelet-Rich Fibrin and Hyaluronic Acid Combination.: 0.5 ml of Commercially available Hyaluronic acid (Hyalgan 20gm/2ml,FIDIA) will be added to 1ml of I-PRF which is prepar

Sponsors

Malya Manoj Kumar Naik
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients in the age group of 18-60 years. 2.Patients diagnosed with Wilkes stage II and III of ID of temporomandibular joint. 3.Patients not responding to conservative treatments. 4.Willingness to participate in the study and to give informed consent. 5.Willing for a minimum 6-month follow-up after undergoing treatment.

Exclusion criteria

Exclusion criteria: 1.Any systemic or malignant disease that could interfere with the TMJ treatment or assessment. 2.History of Previous TMJ surgery/condylar trauma. 3.Failure during intra-articular injection procedure. 4.Fibrous or osseous ankylosis of the TMJ. 5.Cutaneous, otic, or articular infections. 6.Edentulous patients. 7.Pregnant and breastfeeding. 8.Bilateral TMJ pain.

Design outcomes

Primary

MeasureTime frame
1.Pain at rest & chewing, assessed by means of a visual analog scale. 2.Mandibular range of movement, comprising maximum non assisted & assisted mouth opening, left & right laterotrusion, & protrusion movements. 3.Clicking by Auscultation. 4.QOL questionnaire. 5.Functional limitation during usual jaw movements.Timepoint: 1.Pain at rest & chewing at 1 Week,1 month,3 months,6 months postoperative. 2.Mandibular range of movement, comprising maximum non assisted & assisted mouth opening, left & right laterotrusion, & protrusion movements at 1 Week,1 month,3 months,6 months postoperative. 3.Clicking at 1 Week,1 month,3 months,6 months postoperative. 4.QOL questionnaire at 1 Week,1 month,3 months,6 months postoperative. 5.Functional limitation at 1 Week,1 month,3 months,6 months postoperative.—

Secondary

MeasureTime frame
1.Pain at rest & chewing, assessed by means of a visual analog scale. 2.Mandibular range of movement, comprising maximum non assisted & assisted mouth opening, left & right laterotrusion, & protrusion movements. 3.Clicking by Auscultation. 4.QOL questionnaire. 5.Functional limitation during usual jaw movements.Timepoint: 1.Pain at rest & chewing at 1 Week,1 month,3 months,6 months postoperative. 2.Mandibular range of movement, comprising maximum non assisted & assisted mouth opening, left & right laterotrusion, & protrusion movements at 1 Week,1 month,3 months,6 months postoperative. 3.Clicking at 1 Week,1 month,3 months,6 months postoperative. 4.QOL questionnaire at 1 Week,1 month,3 months,6 months postoperative. 5.Functional limitation at 1 Week,1 month,3 months,6 months postoperative.—

Countries

India

Contacts

Public ContactDr Kishore Moturi

Vishnu Dental College

shivajiraju.u@vdc.edu.in9966351997

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026