Health Condition 1: 8- Other Procedures
Conditions
Interventions
Control Intervention1: Inj. Tranexamic Acid.: 2 different doses of Inj. Tranexamic Acid.
1. Loading dose 10mg/kg followed by maintenance dose 0.5mg/kg/hr.
2. Loading dose 15mg/kg followed by maintena
Sponsors
Department of Anesthesia Government Medical College Surat
Eligibility
Inclusion criteria
Inclusion criteria: Patients scheduled for spine surgery. Patients belonging to ASA class 1,2 and 3.
Exclusion criteria
Exclusion criteria: Patient who are allergic to tranexamic acid. Patients with altered clotting factors, coagulation profile, coagulation disorders etc. Patients with neurosurgical disorders, epilepsy and visual disturbance. Patients with deep vein thrombosis and thromboembolism. Patients with major hepatorenal dysfunction. Patients with major cardiopulmonary dysfunction, Ischemic Heart Diseases, Angina. Patients taking medications like blood thinners, antiplatelet drugs, anti-coagulants, fibrinolytics drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total intraoperative blood loss. Requirement of blood and blood products in 24 hours. Timepoint: 24 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of: Hemoglobin, Haematocrit and PT INR values pre-operatively and Hemoglobin and Haematocrit 24 hours post-operatively. Hemodynamic parameters. Adverse effects/side effects if any.Timepoint: 24 hours. | — |
Countries
India
Contacts
Public ContactDr Bansari N Kantharia
New Civil Hospital, Surat.
Outcome results
None listed