Health Condition 1: -
Conditions
Interventions
Intervention1: IV Fentanyl: 2mcg/kg in 100ml NS over 15mins
Control Intervention1: IV Ketamine: 2mg/kg in 100ml NS over 15mins
Sponsors
Dr Deekshanth Ramakrishnan
Eligibility
Inclusion criteria
Inclusion criteria: 1)Patients belonging to ASA physical status I and II 2)Age 18-60 years, belonging to either gender 3)Patients giving informed written and valid consent 4)Patients undergoing upper/lower ureteric and urethral procedures under spinal anaesthesia
Exclusion criteria
Exclusion criteria: 1)Patients with diabetes mellitus, chronic renal failure 2)Pregnant females 3)Patients on any drugs causing a delay in gastric emptying like aluminum hydroxide, antacids, calcium channel blockers, diphenhydramine, L-Dopa, lithium and tricyclic antidepressants(TCAs) • Patients on pantoprazole and metaclopramide • Patients having hypersensitivity to any of the study drugs • Patients with prior history of gastrointestinal disease and gastrointestinal reflux disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To detect opioid-induced delay in gastric emptying in the perioperative periodTimepoint: Gastric residual volume will be measured before induction of anaesthesia, immediately after surgery, 2 hours postoperative, 6 hours postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)To find the efficacy of gastric ultrasound as a bedside tool for assessing the quality & quantity of gastric contents in the peri-operative period. 2)To assess the delay in gastric emptying produced by ketamine. 3)To find out if pain produces delay in gastric emptying. Timepoint: Gastric residual volume will be measured just be induction of anaesthesia, immediately after surgery, 2hours postoperative, 6hours postoperative | — |
Countries
India
Contacts
Public ContactDr Madhuri S Kurdi
Karnataka Institute of Medical Sciences
Outcome results
None listed