Health Condition 1: C508- Malignant neoplasm of overlappingsites of breast
Conditions
Interventions
Intervention1: SPECT/ CT lymphoscintigraphy: SPECT/ CT lymphoscintigraphy using Tc99 sulphur colloid to identify critical arm draining lymph node for breast radiation therapy planning to prevent lymph
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Age > 18 years 2. Unilateral breast cancer 3. Post Breast conservation surgery, stage I,IIA and IIB. 4. Patients planned for whole breast radiation F/B tumor bed boost with pathologically N0 disease. 5. Adequate axillary dissection (10-12 nodes dissected) 6. Post op Histopathology-Invasive ductal carcinoma, negative margins, Lymphovascular space invasion â??ve, Extranodal extension -ve
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. Bilateral breast cancer/ recurrent breast cancer 2. Previous radiation therapy to chest wall 3. Active infection in local site, i.e: arm. 4. Predisposing conditions to Lymphedema and lymphadenitis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)To find out the amount of dose reduction to the arm draining lymph node if any, after giving dose constraints in modified plan of RT in early breast cancer patients undergoing breast conserving surgery.Timepoint: At 0 week: Start of Study During course of RT: Review every week. At 26 week:Lymphedema reassessment using LyQLI questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Outcome TimePoints 1)To assess Quality of life using LyQLI questionnaire 6 months post RT 2)To compare the severity of lymphedema between baseline & 6 months post RTTimepoint: At 0 week: Start of Study During course of RT: Review every week. At 26 week:Lymphedema reassessment using LyQLI questionnaire. | — |
Countries
India
Contacts
Public ContactGunaseelan K
Jawaharlal Institute of Postgraduate Medical Education & Research,Puducherry
Outcome results
None listed