A prospective comparative study evaluating the effectiveness of opioid- free anaesthesia in controlling post-operative serum levels of inflammatory markers and offering post-operative anaesthesia for open abdominal hysterectomies.

Evaluation of opioid free anaesthesia in curtailing postoperative serum levels of inflammatory markers and providing post-operative analgesia in open abdominal hysterectomies - A prospective comparative study. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/059938

Enrollment

Registered

2023-11-17

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: The study evaluates the effectiveness of opioid-free anesthesia in reducing post-operative serum levels of immunomodulatory markers and providing post-operative analysis in open abdomin

Eligibility

Inclusion criteria

Inclusion criteria: - women undergoing abdominal hysterectomy - ASA grade I and II - BMI <35 kg/m2

Exclusion criteria

Exclusion criteria: - difficult airway - contraindications to the drugs used.

Design outcomes

Primary

Measure	Time frame
The inflammatory markers of a total 60 sample size would be studied to compare the effectiveness of opioid based vs opioid free anaesthesia.Timepoint: Initial pre-operative inflammatory markers will be compared to a 24 hr post operative inflammatory marker levels.	—

Secondary

Measure	Time frame
1- To compare the serum levels of post-operative inflammatory markers in patients receiving anaesthesia by the 2 different anesthetic procedures. 2- To compare pain score & duration of postoperative analgesia in the 2 groups. 3- To compare the incidence of post-operative nausea & vomiting.Timepoint: post-operative pain , nausea & vomiting will assessed over a 24 hrs period with 4 hr intervals	—

Countries

India

Contacts

Public ContactDr Vidya Patil

BLDE- Shri B M patil medical college and hospital

vidyapatila@gmail.com9448131260

Outcome results