in proposed study effect of nebulisation with magnesium sulphate , ketamine and lignocaine on heart rate and blood pressure during endotracheal intubation will be observed

comparison of haemodynamics changes after nebulization with ketamine , magnesium sulphate and lignocaine for endotracheal intubation in general anaesthesia - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/059926

Enrollment

Registered

2023-11-16

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems

Interventions

Intervention1: endotracheal intubation in patient scheduled for general anaesthesia: endotracheal intubation will be done and effect of comparator agents on hemodynamics will be recorded at 1 ,2 , 3

Eligibility

Inclusion criteria

Inclusion criteria: Patients in age group of 18-60 years American Society of Anaesthesiologists (ASA) Status I and II Patients undergoing elective surgery requiring general anaesthesia with endotracheal intubation

Exclusion criteria

Exclusion criteria: Patients with difficult airway with Airway difficulty score >8 Morbid obesity BMI > 35 kg/m 2 Known airway pathology Oropharyngeal surgeries Surgery duration more than 3 hours Patients at increased risk of aspiration like GERD, peptic ulcer Previous upper gastrointestinal surgery Known or anticipated difficult tracheal intubation or facemask ventilation Coagulopathy or history of anticoagulant use Cardiorespiratory or cerebrovascular disease Cervical spine injury 12. Pregnant Patients

Design outcomes

Primary

Measure	Time frame
Comparison of haemodynamic changes after nebulization with Ketamine, Magnesium Sulphate and lignocaine for endotracheal intubation in general anaesthesia.Timepoint: 1 , 2 ,3 , 5, 10 minutes	—

Secondary

Measure	Time frame
To compare the effect of nebulization of ketamine, magnesium sulfate and lidocaine on postoperative sore throat in patients after endotracheal intubation.Timepoint: post operative sore throat grading	—

Countries

India

Contacts

Public ContactDr Manpreet Singh

Gmch 32 Chandigarh

manpreetdawar@gmail.com9646121503

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026