Health Condition 1: R90-R94- Abnormal findings on diagnostic imaging and in function studies, without diagnosis
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
MES Dental College
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with complete dentition apart from third molars 2. Patients in the age group 15 – 30 yrs. 3. Group 1 patients will include Patients with Angle’s Class I bimaxillary dentoalveolar protrusion indicated for fixed appliance treatment with therapeutic extraction of first premolar teeth in the maxillary arch. 4. Group 2 patients with Angle’s Class I bimaxillary dentoalveolar protrusion indicated for fixed appliance treatment with therapeutic extraction of first premolar teeth in the maxillary arch, with increased visibility of maxillary anteriors >4mm. 5. Patients should be having healthy gingival and periodontal status 6. Patients with no radiographic evidence of root resorption after a full mouth radiographic periapical examination
Exclusion criteria
Exclusion criteria: 1. Missing molars or any of the anterior teeth 2. Previous history of orthodontic treatment 3. Erupted or unerupted supernumeraries in the maxillary anterior segment 4. Impacted canines, Endodontically treated teeth 5. Upper anterior crowding = 4mm 6. Periodontitis 7. History of avulsion or replantation 8. History of prolonged treatment with systemic steroids and NSAIDs 9. History of metabolic disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMP-9 is expressed as an extracellular matrix protein by osteoclast. Its presence often indicates an active bone/root resorption which indicated tooth movement. Bone resorption appears in radiographs at a later stage of treatment. The early detection of MMP-9 in the gingival crevicular fluid occurs at an earlier stage and can be taken as a predictive marker for active bone/tooth resorption.Timepoint: TO- Before treatment T1-Beginning of retraction (6-9months) T2-Three months after start of retraction (9-12months) | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of the extent of root resorption at three months following the start of retraction.Timepoint: TO- Before treatment T2-Three months after start of retraction (9-12months) | — |
Countries
India
Contacts
Public ContactRishika EK
MES Dental College, Kerala
Outcome results
None listed