Health Condition 1: J17- Pneumonia in diseases classified elsewhere
Conditions
Interventions
Intervention1: Probiotic: 1 capsule of Bifidobacterium(1.0 B) + Lactobacillus Acidophilus(1.0 B) given via ryles tube or per oral twice daily (1-0-1) for 7 days and patient will be observed for incide
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: All critically ill patients of at least 18 years of age who were mechanically ventilated with an endotracheal tube for more than 48 hours.
Exclusion criteria
Exclusion criteria: Previous history of immunosuppression, prosthetic cardiac valve or valvular graft, rheumatic fever, recent gastroesophageal or intestinal injury/surgery, tracheostomy, patient refusal. Patient having pregnancy/pneumonia currently, severe multiple organ failure with Acute Physiology and Chronic Health Evaluation (APACHE) II score of more than or equal to 25 & Mechanical ventilation for more than 72 hours prior to enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of probiotics on preventing VAP, and other clinically important outcomes in the intensive care unit (ICU)Timepoint: 14 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of Mechanical Ventilation Timepoint: 31 days;Incidence of constipation/diarrhea Timepoint: 14 days;Length of stay in ICUTimepoint: 31 days | — |
Countries
India
Contacts
Public ContactTushar Aneja
Bharati Vidyapeeth Deemed to be University
Outcome results
None listed