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Comparison between two different drugs in laproscopic surgery under general anesthesia

Comparison between opioid free Anesthesia and opioid based anaesthesia for patients undergoing laparoscopic surgeries under general anaesthesia. A double blinded randomized control trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/059905
Enrollment
100
Registered
2023-11-16
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis

Interventions

Intervention1: Lidocaine and dexmedetomidine infusion: Inj lidocaine infusion 1.5 mg/ kg bolus (diluted to 5 ml with NS ) and dexmedetomidine 0.6 mcg/kg bolus (diluted to 5 ml NS ) will be given to pa

Sponsors

S Nijalingappa Medical College and HSK Hospital.
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA physical status 1 and 2 2.Age between 18 to 65 years 3.Patients undergoing laparoscopic surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.History of opioid use 1 month prior to surgery 2.chronic opioid addiction 3.Inability to comprehend visual analogue scale 4.history of significant hepatic renal and cardiac disease 5.history of chronic pain and drug abuse

Design outcomes

Primary

MeasureTime frame
To compare the heart rate and mean arterial pressure intraoperative with continuous lidocaine and dexmedetomidine infusion as opposed to conventional opioid based anaesthesiaTimepoint: 24 hours—

Secondary

MeasureTime frame
1.postoperative pain in first 24 hours and time to rescue analgesia is compared in both groups 2.postoperative nausea vomiting assessment in both groups 3.sedation scoring in one after extubation will be assessed in both groups using Ramsay sedation scoringTimepoint: 24 hours—

Countries

India

Contacts

Public ContactDRDARSHINI T K

S.Nijalingappa Medical College and HSK Hospital, Navanagar, Bagalkot.

darshinikrishnamurthy@gmail.com7411674099

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026