Health Condition 1: M995- Intervertebral disc stenosis of neural canal
Conditions
Interventions
Intervention1: Transforaminal Epidural Injection: Dose: 5 mg of Etanercept
Frequency: Once
Route: Transforaminal Epidural
Duration: 10 minutes
Control Intervention1: Tumour necrosis Factor Alpha (TNF
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: 1. History of segmental low back pain of lumbar origin with or without radiation to the unilateral lower limb below the knee of more than 3 months duration. 2. History of predominant leg pain over back pain. 3.Radicular pain not responding to oral medications and physiotherapy. 4. Pain involving up to two segmental levels in lumbar area. 5. Average pain score of =5 on an 11-point NRS. 6.Computed tomography/Magnetic resonance imaging evidence of nerve root pain
Exclusion criteria
Exclusion criteria: 1. Patient refusal to participate. 2. History of previous back surgery or steroid injections 3. Severe spinal stenosis. 4. Any condition known to be amenable to TNF-alpha inhibitors e.g Spondyloarthropathy and chron’s disease. 5. Systemic infections or Infection at the site of injection. 6. Contrast allergy Or local anaesthetic allergy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease in Pain Score measured by NRSTimepoint: before procedure immediate post procedure 2week 1month 2months & 3months post procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Oswestry Disability QuestionnaireTimepoint: before procedure After procedure 2 weeks 1 month 2 months & 3 months;TNF alphaTimepoint: before intervention & 2 week after intervention | — |
Countries
India
Contacts
Public ContactSukhdeo Satyanarayan Gupta
All India Institute of Medical Science Rishikesh
Outcome results
None listed