A study to evaluate the effect of an ayurvedic treatment protocol prior to in vitro fertilization in women with diminished ovarian reserve and understanding the molecular mechanisms involved.

Role of an ayurvedic treatment protocol as a prerequisite for in vitro fertilization in women with diminished ovarian reserve: elucidating mechanistic insights incorporating multi-omics approaches - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/059872

Enrollment

Registered

2023-11-15

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N979- Female infertility, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1)Participant willing and able to give informed consent for participation in the trial. 2)Diagnosed with Diminished ovarian reserve (serum AMH 3)Poor ovarian response in the prior IVF cycle

Exclusion criteria

Exclusion criteria: 1)Diagnosed of genetic disorders 2)Undergoing treatment for malignancy 3)History of oophorectomy

Design outcomes

Primary

Measure	Time frame
1) Improvement in Ultrasonography count of ovarian antral follicles, Antral follicle count (AFC) - on Day 2/3 of the menstrual cycle 2)Improvement in serum anti-Mullerian hormone (AMH) – Day 2/3 of the Menstrual CycleTimepoint: Assessment before treatment (BT) will be done during recruitment and post assessment after treatment (AT) will be done after two months of Ayurvedic treatment.	—

Secondary

Measure	Time frame
Multi omics analysis of follicular fluid - (Treatment group - 10; after two months of Ayurveda treatment and Control group - 10).Timepoint: On the day of oocyte retrieval during In Vitro fertilization.	—

Countries

India

Contacts

Public ContactDr Muralidharan V

Amrita School of Biotechnology

muralidharanv89@gmail.com8589083013

Outcome results