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Post operative pain relief using Buprenorphine and Ketorolac

A Randomized control study of post-operative analgesic effect of Buprenorphine and Ketorolac in elective abdomen surgeries under General Anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/059855
Enrollment
140
Registered
2023-11-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K353- Acute appendicitis with localizedperitonitis Health Condition 2: K400- Bilateral inguinal hernia, with obstruction, without gangrene Health Condition 3: K811- Chronic cholecystitis

Interventions

Intervention1: Inj. Buprenorphine: 4 micrograms/kg body weight intra muscular at the end of the surgery. One single dose Intervention2: Inj. Ketorolac: 0.9mg/kg body weight intra muscular at the end

Sponsors

Kameshwar ownself
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I or II 2. Patients scheduled for elective abdomen surgeries under general anesthesia 3. Age: 20-60 years

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Allergy or hypersensitivity to Buprenorphine and Ketorolac. 3. Pregnant and Lactating women 4. Patient having a. Uncontrolled hypertension/diabetes mellitus. b. Cardiac disease, Hepatic diseases, renal diseases. c. History of chronic pain. d. Psychiatric disease. e. Alcohol or drug usage.

Design outcomes

Primary

MeasureTime frame
1.Dose of the study drug 2.Time duration needed for the usage of rescue analgesic Timepoint: Baseline ( before the surgery), Intra operative period, Immediate post operative period-0 minutes 1 hour after post operative period, 2 hours after post operative period, 4 hours after post operative period, 6 hours after post operative period, 8 hours after post operative period, 12 hours after post operative period.

Secondary

MeasureTime frame
Time duration for rescue analgesicTimepoint: At the end of surgery 0 hours, 1 hour after surgery, 2 hours after surgery, 4 hours after surgery, 6 hours after surgery, 8 hours after surgery, 12 hours after surgery.

Countries

India

Contacts

Public ContactKameshwar

Srimuthukumaran Medical College

ramkumar.pal@gmail.com9840744672

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026