Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Entropy guided Sevoflurane administration: In one group of patients, Sevoflurane (Volatile anaesthetic) will be delivered to the patient, adjusted according to Entropy value (target ent
Sponsors
Armed Forces Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients undergoing elective on pump cardiopulmonary bypass surgery 2.Written and informed consent
Exclusion criteria
Exclusion criteria: 1. An active infection of temperature > 38 degrees centigrade 2. History of a neurological disease 3. Previously diagnosed Renal and Hepatic disorder 4. Emergency surgery 5. Any kind of diagnosed or suspected syndrome 6. Deep Hypothermic circulatory arrest
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in sevoflurane end oxygenator concentration with entropy guided sevoflurane administrationTimepoint: At the time of induction At the time of skin incision At the time of sternotomy At the time of starting of CPB At the time of Cross clamping of Aorta At 10min intervals during CPB At the time of removal of Cross clamp from Aorta At the time of stopping of CPB At the time of skin Closure | — |
Secondary
| Measure | Time frame |
|---|---|
| IBP MAP CPB FLOW SEVOFLURANE Dial Concentration (%w/v) Body Temperature ETCO2 FiO2 VISTimepoint: AT 10 min intervals during CPB | — |
Countries
India
Contacts
Public ContactDr Rahul Yadav
Armed Forces Medical College
Outcome results
None listed