The effect of dexmedetomidine addition to levobupivacaine-epinephrine in ultrasound guided bilateral superficial cervical plexus bock on post oprative analgesia in patients undergoing thyroid surgery under general anaesthesia.

The effect of dexmedetomidine addition to levobupivacaine-epinephrine in ultrasound guided bilateral superficial cervical plexus bock on post oprative analgesia in patients undergoing thyroid surgery under general anaesthesia: a randomized controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/059843

Enrollment

Registered

2023-11-15

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: E078- Other specified disorders of thyroid

Interventions

Intervention1: 0.25% levobupivacaine with 5 mcg/ml epinephrine in bilateral superficial cervical plexus block: After induction by general anaesthesia, using levobupivacaine(0.25%)- epinephrine (5 mcg/

Eligibility

Inclusion criteria

Inclusion criteria: Patient giving written informed consent will be taken who are scheduled for elecive thyroid surgery includng goiters, tumours and cyst with euthyroid confirmed with thyroid function tests(TSH, free triidothroxine, thyroxine) Aged 20-65 years and ASA physiological status I and II undergoing general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Refusal of patient. 2. those patients in whom endotracheal tube was retained after surgery. 3. those who could not comprehend numerical pain score. 4. patients having concomitant disease interfering with post operative assessment, pre existing peripheral nerve neuropathies, substernal goiter, probable cervical lymph node dissection. 5. patient on adrenoreceptor agonist or antagoinst treatment. 6. patients having allergic reactions to levobupivacaine, epinephrine or dexmedetomedine.

Design outcomes

Primary

Measure	Time frame
Post operative pain intensity by Visual analog scale. Total analgesic requirement in first 24 hours. Timepoint: Total analgesic requirement in first 24 hours.	—

Secondary

Measure	Time frame
Hemodynamics(HR, DBP, SBP, MAP, SPO2)Timepoint: Hemodynamics(HR, DBP, SBP, MAP, SPO2) at 0,2,4,6,12,24 hours	—

Countries

India

Contacts

Public ContactDR MANISH KUMAR SINGH

KING GEORGE MEDICAL UNIVERSITY

manish.is.singh34@gmail.com7905303840

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026