Health Condition 1: N17- Acute kidney failure Health Condition 2: K74- Fibrosis and cirrhosis of liver Health Condition 3: R188- Other ascites
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
Deep Patel
Eligibility
Inclusion criteria
Inclusion criteria: Decompensated Cirrhosis with ascites having AKI (=Stage IB, Serum creatinine=1.5mg/dl)
Exclusion criteria
Exclusion criteria: 1) Advanced Chronic Kidney Disease 2) Prior Kidney or Liver Transplant 3) Renal Replacement Therapy at the time of enrolment 4) Pregnancy 5) Diagnosed case of Hepatocellular carcinoma 6) Extrahepatic Malignancy 7) Severe Co-morbidities (CHF, COPD)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity, Specificity, Positive predictive value, Negative predictive value and diagnostic accuracy of Urine NGAL and Urine IL-18 in decompensated cirrhotic patients having Acute Kidney injury for differentiating between ATN-AKI vs Non-ATN-AKI.Timepoint: At baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity, Specificity, Positive predictive value, Negative predictive value & diagnostic accuracy of Urine NGAL & Urine IL-18 in decompensated cirrhotic patients having Acute Kidney injury for differentiating between HRS-AKI vs Non-HRS-AKI.Timepoint: At baseline;Sensitivity, specificity, Positive predictive value, Negative predictive value & diagnostic accuracy of Urine NGAL & Urine IL-18 in decompensated cirrhotic patients having Acute Kidney injury for differentiating between PRA-AKI vs Non-PRA-AKI.Timepoint: At baseline | — |
Countries
India
Contacts
Public ContactDeep Patel
Govind Ballabh Pant Hospital, New Delhi
Outcome results
None listed