Comparison between normal denture vs chitosan modified dentures for candidal count and retention

Comparative evaluation of candidal count and retention in patients wearing maxillary complete dentures fabricated using 5% (low molecular weight) chitosan modified heat polymerized PMMA resin and conventional heat polymerized PMMA resin : a randomised cross over clinical study - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/059783

Enrollment

Registered

2023-11-14

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K069- Disorder of gingiva and edentulousalveolar ridge, unspecified

Interventions

Intervention1: Conventional heat polymerized PMMA resin: Polymethyl methacrylate (PMMA) resin is the conventional material used for fabrication of denture base Control Intervention1: 5% chitosan (low

Eligibility

Inclusion criteria

Inclusion criteria: A.Completely edentulous participants requiring removable complete denture B.Patients with Type A Maxillary residual ridge morphology and class 1 complete edentulism based on the American college of prosthodontics(ACP) classification C.Patients with no anterior and/or posterior undercuts

Exclusion criteria

Exclusion criteria: A.Patients with implants or overdenture abutments in upper arch B.Absence of any local and systemic disease that produce oral manifestation C.Patients with excessive gag reflex D.Patients with reduced salivary flow or having xerostomia E.Patients with known allergy to denture base material(PMMA) F. Patients with known allergy to chitosan microparticles G.Patients having any surgical or congenital maxillary defects H.Patients who are not willing to sign the consent form

Design outcomes

Primary

Measure	Time frame
Candidal count testing Retention testingTimepoint: Baseline,4 weeks,10 weeks.	—

Secondary

Measure	Time frame
N/ATimepoint: N/A	—

Countries

India

Contacts

Public ContactDr Rushabh Bafna

K M SHAH DENTAL COLLEGE HOSPITAL

drnamrata@live.in9909312360

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026