A study to compare effectiveness of Fractional Co2 laser with Platelet rich plasma (PRP) Versus Microneedling with PRP in treatment of Acne scars

A Split-face Comparative study on efficacy of Fractional CO2 Laser with PRP vs. Microneedling with PRP in Treatment of Atrophic Acne Scars - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/059775

Enrollment

Registered

2023-11-14

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L905- Scar conditions and fibrosis of skin

Interventions

Intervention1: Microneedling with Platelet rich Plasma (PRP): This is a split face study in which the patients will be randomized to receive fractional CO2 laser over one side of face, while the other

Eligibility

Inclusion criteria

Inclusion criteria: (i) Patients above the age of 18 years. (ii) Patients with acne scars with > 2 points on Goodman and baron’s quantitative global acne scarring grading system over both side of face. (iii) Patients who are willing to undergo the evaluation system and able to comply with all follow-up requirements.

Exclusion criteria

Exclusion criteria: (i) Patients with active acne or any local site infection. (ii) Patients with acne scars with = 2 points on Goodman and baron’s quantitative global acne scarring grading system over any side of face. (iii) Patients below 18years and above 60 years (iv) Patients not willing for the procedure. (v) Patients having keloid or keloidal tendency (vi) Patients who have taken isotretinoin within 06 months or have undergone laser treatment or Microneedling over face within previous 01 year. (vii) Any serious medical condition including bleeding diathesis, platelet disorders or in immunocompromised state. (viii) Patients with past history of herpes infection. (ix) Pregnant and lactating mothers. (x) Patients with unrealistic expectations.

Design outcomes

Primary

Measure	Time frame
To assess which modality is more efficacious in the treatment of Atrophic Acne scars i.e. Fractional CO2 laser with PRP or Microneedling with PRPTimepoint: After completion of study i.e. one and half years	—

Secondary

Measure	Time frame
a) To asses the effectiveness of Fractional CO2 laser with PRP for treatment of Atrophic Acne scars. b) To asses the effectiveness of Microneedling with PRP for treatment of Atrophic Acne scars. c) To asses the side-effect profile & safety of Fractional CO2 laser with PRP & Microneedling with PRP therapy.Timepoint: After completion of study i.e. one & half years	—

Countries

India

Contacts

Public ContactDr Sanoj

Command Hospital Air Force Bangalore

debdeep5000@gmail.com7051891307

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026