Health Condition 1: G891- Acute pain, not elsewhere classified
Conditions
Interventions
Intervention1: Group M (Melatonin): Interventional group (Group M) will be given Melatonin 6mg tablet Orally once daily at night 3 days prior to Surgery, 1 hour before surgery and on the night of su
Sponsors
AIIMS Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: ASA I & II patients planned for elective spinal fusion surgery (one or two levels)
Exclusion criteria
Exclusion criteria: Refusal to give consent, Spinal fusion surgery involving cervical spine and at different sites, Allergy to Melatonin, Pregnancy, BMI > 30kg/m2, Use of narcotic painkillers, gabapentin and tricyclic antipsychotics 72 hours before the intervention, history of any psychiatric disorder, chronic hepatic or renal disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to request for 1st rescue analgesia in the postoperative periodTimepoint: 1st 24 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| CRP and IL-6 levelsTimepoint: preoperative and 24 hours postoperative;QOR 15 ScoreTimepoint: preoperative and 24 hours postoperative;Total amount of analgesics (Intravenous Tramadol in milligrams)Timepoint: 1st 24 hours postoperatively;VAS ScoreTimepoint: 1 hour, 6 hour, 12 hour, 24 hour postoperatively | — |
Countries
India
Contacts
Public ContactDr Aparajita Panda
AIIMS Bhubaneswar
Outcome results
None listed