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Evaluation of levels of Biomarkers in different stages of Pulpitis

Molecular Approaches to develop Objective Diagnostic Tools in Vital Pulp Treatment - VPT

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/059706
Enrollment
120
Registered
2023-11-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Full Pulpotomy: Full pulpotomy procedure will be done by complete removal of inflamed pulp tissue from the pulp chamber which will take 60 to 70 minutes Control Intervention1: Partial P

Sponsors

Manipal College of Dental Sciences
Lead Sponsor
Manipal College of Dental Sciences Manipal
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients with a healthy unrestored sound tooth premolars or molars with no signs of resorption or periodontal disease that is indicated for extraction for orthodontic purposes Adult patients presenting with a deep or extremely deep carious lesion radiographically reaching close to the pulp inner quarter of dentine and signs and symptoms ranging between mild moderate and severe pain Positive response to cold and electric pulp sensibility test and pulpal exposure during non selective removal of caries

Exclusion criteria

Exclusion criteria: More than 3mm periodontal probing depth for tooth of interest Severe case of pulpitis where time taken to achieve haemostasis is more than 10mins Necrotic pulp Systemic conditions like Bleeding disorders uncontrolled hypertension diabetes patients on anticoagulant therapy

Design outcomes

Primary

MeasureTime frame
Vitality of pulpotomised toothTimepoint: 1 year

Secondary

MeasureTime frame
Levels of biomarkers in pulp tissueTimepoint: 1 year

Countries

India

Contacts

Public ContactDr Narkedamalli Raj Kumar

Manipal Academy of Higher Education MAHE Manipal

drballal@yahoo.com9880626167

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026