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Effectiveness of 2 different medications in reducing of swelling, trismus and pain after mandibular third molar extraction.

Effectiveness of intra-socket application of dexamethasone soaked gelfoam and injection hyaluronic acid soaked gelfoam following mandibular third molar extraction. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/059700
Enrollment
54
Registered
2023-11-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Extraction of mandibular third molar: The procedure will be carried out by the surgical team and local anaesthesia (LA with 2% adrenaline) will be given for the lower third molar which

Sponsors

Manipal college of dental sciences manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with previous dental symptoms (for example, acute pericoronitis, pain, or caries of the second or third molar due to malposition or impaction resulting in the retention of food).

Exclusion criteria

Exclusion criteria: 1. Patients younger than 18 years old or older than 50 years old. 2. Patients with disabilities, allergies, and/or intolerances to the medications used in the study. 3. Patient undergoing anticoagulant, oncological or bisphosphonate treatment. 4. Patient with any systemic pathology that could affect the effect. 5. Patient with wisdom teeth and associated odontogenic cysts or active infection. 6. Patients who have received locoregional radiation therapy or prior surgery on the lower retromolar trigone 7. Pregnant women 8. Anyone who did not wish to participate in the study or did not authorize their participation.

Design outcomes

Primary

MeasureTime frame
Decrease in post-operative pain and trismus and oedema after lower third molar extraction in all the groups- gelfoam alone, dexamethasone soaked gelfoam and Injection Hyaluronic acid soaked gelfoam. Timepoint: Measurements of swelling, trismus and post-operative pain will be done immediately just before the surgery,third and seventh day.

Secondary

MeasureTime frame
Decrease in usage of medications & acceleration of wound healing in all the groups.Timepoint: Medications & acceleration of wound healing will be recorded on third & seventh day

Countries

India

Contacts

Public ContactDr Chithra A

Mcods, Manipal

chitra.a@manipal.edu9481939772

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026