Health Condition 1: K135- Oral submucous fibrosis
Conditions
Interventions
Intervention1: Propolis: Topical application of Propolis thrice daily for 6 months.Follow up at regular interval of 4 weeks up to 6 months.
Control Intervention1: Triamcinalone acetonide: Topical app
Sponsors
Maulana Azad Institute of Dental Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Clinically & histopathologically proven cases of OSMF and OLP and OSCC Any subject of age group18 to 50 years. Both males and females. A positive history of chewing areca nut or one of its commercial preparation, difficulty in swallowing and chewing, and burning sensation on eating spicy foods.(osmf) Restricted mouth opening and changes in the oral mucous membrane including the presence of palpable vertical fibrous bands, stiffness and blanching.(osmf)
Exclusion criteria
Exclusion criteria: Subjects with mouth opening less than 15 mm. Subjects with systemic diseases, immunocompromised patients and patients who are taking medications which may effect the result of the study. Pregnant and nursing women. Subjects who are known allergic to honey bees or bee products. Those patients who are not willing to participate in study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mouth Opening, Tongue Protrusion, Cheek flexibility, VAS score,pain score.Timepoint: 4 weeks up to 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate whether topical propolis can be used as an alternative to topical triamcinolone acetonide for treating OPMDs . Timepoint: 4 weeks up to 6 months | — |
Countries
India
Contacts
Public ContactDR SUJOY GHOSH
MAULANA AZAD INSTITUTE OF DENTAL SCIENCES
Outcome results
None listed