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Gum disease and migraine

INVESTIGATING THE ROLE OF NEOPTERIN IN MIGRAINEURS WITH CHRONIC PERIODONTITIS - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/11/059694
Enrollment
68
Registered
2023-11-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G00-G09- Inflammatory diseases of the central nervous system

Interventions

None listed

Sponsors

SRM Dental College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with minimum 15 teeth or more exhibiting generalized chronic periodontitis patients (pocket depth >4mm and CAL of >3mm in more than 30% diseased sites,(According to the AAP classification 2017 stage III grade B in group I and stage III grade C in group II) and previously documented patients to be able to predict migraines from pre-monitory symptoms as defined by IHS (International headache society )18 experiencing average of between one and six migraines per month not on preventative medications were included in the study

Exclusion criteria

Exclusion criteria: . Exclusion criteria’s were diabetes, blood dyscrasias, gross oral pathology, smoking, alcoholism, anomalies of the immune system, medications that would affect periodontal and neurological status, and previous or current periodontal therapy

Design outcomes

Primary

MeasureTime frame
1. Plaque Index (Sillness and Loe, 1964)(PI) 2.Gingival Index(Loe and Sillness,1963)(GI) 3.Bleeding on probing(BOP) 4.Probing Depth (PD) 5.Clinical attachment level (CAL) Timepoint: Baseline

Secondary

MeasureTime frame
To measure the serum and salivary levels of neopterin in patients with chronic periodontitis and chronic migraine to estabalish a correlation between them.Timepoint: BASELINE

Countries

India

Contacts

Public ContactDr Vinu Ramasundaram

SRM DENTAL COLLEGE

deepa_ponnaiyan@yahoo.co.in9884358568

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026