Health Condition 1: G00-G09- Inflammatory diseases of the central nervous system
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subjects with minimum 15 teeth or more exhibiting generalized chronic periodontitis patients (pocket depth >4mm and CAL of >3mm in more than 30% diseased sites,(According to the AAP classification 2017 stage III grade B in group I and stage III grade C in group II) and previously documented patients to be able to predict migraines from pre-monitory symptoms as defined by IHS (International headache society )18 experiencing average of between one and six migraines per month not on preventative medications were included in the study
Exclusion criteria
Exclusion criteria: . Exclusion criteria’s were diabetes, blood dyscrasias, gross oral pathology, smoking, alcoholism, anomalies of the immune system, medications that would affect periodontal and neurological status, and previous or current periodontal therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Plaque Index (Sillness and Loe, 1964)(PI) 2.Gingival Index(Loe and Sillness,1963)(GI) 3.Bleeding on probing(BOP) 4.Probing Depth (PD) 5.Clinical attachment level (CAL) Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| To measure the serum and salivary levels of neopterin in patients with chronic periodontitis and chronic migraine to estabalish a correlation between them.Timepoint: BASELINE | — |
Countries
India
Contacts
SRM DENTAL COLLEGE