Role of Ayurvedic medicines and Rasayana therapy for the management of Latent tuberculosis in Indian Population

Promotion of Ayurvedic Medicine and Rasayana Therapy for management of (LTBI) Latent Tuberculosis in Indian Population - Nill

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/059681

Enrollment

1000

Registered

2023-11-08

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z22- Carrier of infectious disease

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Either sex, age between 18-60 years. Untreated Latent Tuberculosis Infection (LTBI), defined as positive QuantiFERON TB Gold test. Induration > 10mm in Mantoux (tuberculin skin) test. No previous history of ATT use/ active tuberculosis (pulmonary/ extra-pulmonary). Absence of active TB disease as determined by sputum smear and/or culture, CBNAAT, chest X-ray, history and physical examination.

Exclusion criteria

Exclusion criteria: A subject will be excluded if any of the following criteria are met: Presence of active TB disease. BMI Uncontrolled hypertension (Systolic >180 mm/Hg or Diastolic >100 mm/Hg)/ having acute coronary syndrome. Chest X-Ray report within last 3 months not available and patient is not willing to carry out fresh investigations. HIV positive and taking ART. Pregnant women, lactating mothers or those who expect to become pregnant for the duration of the study. Hyperpyrexia (temperature =38.5°C). History of antitubercular treatment. Patients having deranged renal functions (any known history of acute/ chronic renal failure).

Design outcomes

Primary

Measure	Time frame
Subjective data study: Prevalence rate of LTBI in selected population of India Clinical manifestations of LTBI % of LTBI subjects having infertility with gender wise distribution Immune status of individual suffering from LTBI Practical efficacy of OJA scale in determining the immunity & severity of disease. Impact of LTBI on individual well being Objective data study: Cure rate (% of TB Gold test become negative after treatment with the Ayurvedic medicines). % improvement in clinical manifestations. Recurrence rate during follow-up duration Maximum & minimum duration of treatment required for the conversion of TB Gold negative. Timepoint: 3 years	—

Measure

Time frame

Subjective data study: Prevalence rate of LTBI in selected population of India Clinical manifestations of LTBI % of LTBI subjects having infertility with gender wise distribution Immune status of individual suffering from LTBI Practical efficacy of OJA scale in determining the immunity & severity of disease. Impact of LTBI on individual well being Objective data study: Cure rate (% of TB Gold test become negative after treatment with the Ayurvedic medicines). % improvement in clinical manifestations. Recurrence rate during follow-up duration Maximum & minimum duration of treatment required for the conversion of TB Gold negative. Timepoint: 3 years

—

Secondary

Measure	Time frame
Information about Yoga (Pranayama) techniques for maintaining lungs good health & lung rehabilitation in post TB subjectsTimepoint: 3 YEARS	—

Countries

India

Contacts

Public ContactDivya Kajaria

All India Institute of Ayurveda

divyakajaria@gmail.com8826167515

Outcome results