Health Condition 1: D000- Carcinoma in situ of lip, oral cavity and pharynx Health Condition 2: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Pavithra V
Eligibility
Inclusion criteria
Inclusion criteria: For Tissues Group 1 Well Diffrentiated Oral Squamous Cell Carcinoma Group2 Moderate and Poorly Diffrentiated Oral Squamous Cell Carcinoma For Saliva Group 1 Well,Moderate,Poorly differentiated and recurrent cases of Oral Squamous Cell Carcinoma Group 2 Premalignant lesions showing moderate and severe dysplasia Group 3 Clinically healthy individuals without any systemic diseases
Exclusion criteria
Exclusion criteria: Patients with systemic diseases, inflammatory oral lesions, periodontal disease, Prior history of other malignancy, Prior treatment in the form of chemotherapy, radiotherapy, Pregnancy, Lactating mothers, Patients who are obese (BMI =30).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 The levels of chemerin in the saliva of healthy individuals, oral epithelial dysplasia and oral cancer patients can be studied and variability among the groups can help in the early diagnosis of oral squamous cell carcinoma 2 The immunohistochemical expression of the chemerin and CD34 in different histological grades of Oral Squamous Cell Carcinoma can be observed and prognostication of patients can be studied Timepoint: 1 year, 2 year | — |
Secondary
| Measure | Time frame |
|---|---|
| The salivary chemerin levels, immunohistochemical expression of chemerin,CD34 with clinicopathological parameters of patients with Oral Squamous Cell Carcinoma can be stratified into low risk,high risk groups for early diagnosis,prognostication.Timepoint: 1 Year, 2 year | — |
Countries
India
Contacts
Public ContactPavithra V
Manipal College Of Dental Sciences
Outcome results
None listed