Comparison of effectiveness Placental extract gel versus Turmeric gel in Mouth Ulcer

Comparison of the efficacy of placental extract gel versus curcumin gel in the treatment of Recurrent aphthous ulcer: A Randomized Clinical Trial - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/11/059637

Enrollment

Registered

2023-11-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: placental extract gel (placentrex): 0.5-1mg of gel applied topically over the ulcer area 3 times daily after the meal for 7 days Control Intervention1: curcuma oral gel (cureNext): 0.5-

Eligibility

Inclusion criteria

Inclusion criteria: patient who are reporting with ulcer that appear less than 48 hours duration. patient with a history of recurrent aphthous ulcer with at least 2 previous episodes were included. patients who are willing to take the treatment of aphthous ulcer & for the scheduled follow - ups.

Exclusion criteria

Exclusion criteria: patient suffering from any disease patient allergic to drug material pregnant woman& lactating mothers subjects with alcohol abuse& tobacco habits patient consuming NSAIDS, topical corticsteroids,immunomodulatory agents, systemic antibiotics, patient on any other intraoral topical medication were excluded.

Design outcomes

Primary

Measure	Time frame
decreased VAS pain score decrease in ulcer size reduction of erythema & exudation levelTimepoint: baseline 1st day 3rd day 7 th day	—

Secondary

Measure	Time frame
recurrence rate of ulcerTimepoint: 1 st month 2 nd month 3 rd month 6 th month	—

Countries

India

Contacts

Public ContactDr Seemadevi T

NIMS University

naganandini36@gmail.com7397625491

Outcome results