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Comparing Injection Palonosetron alone and Palonosetron with Dexamethasone for preventing vomiting in post operation period in cholecystectomy patients

A Comparative Study of the Antiemetic Efficacy of Intravenous Palonosetron Versus Palonosetron with Dexamethasone for the Prevention of Postoperative Nausea and Vomiting Following Laparoscopic Cholecystectomy Under General Anaesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/11/059627
Enrollment
120
Registered
2023-11-07
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Dr SHIVAKUMAR G
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.PATIENTS BETWEEN AGE GROUP 18 YEARS TO 60 YEARS 2.PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY SURGERIES UNDER GENERAL ANAESTHESIA 3.PATIENTS BELONGING TO AMERICAN SOCIETY OF ANAESHESIOLOGISTS PHYSICAL STATUS GRADE I AND II 4.PATIENTS WILLING TO GIVE INFORMED CONSENT TO PARTICIPATE IN THE STUDY

Exclusion criteria

Exclusion criteria: 1.RECEIVED ANTI EMETIC DRUGS OR DRUGS WITH ANTI EMETIC PROPERTY 24 HOURS BEFORE ANAESTHESIA 2.PATIENTS WITH HISTORY OF MOTION SICKNESS 3.PATIENTS WITH BODY MASS INDEX MORE THAN 30 4.PATIENTS WITH HISTORY OF GASTRO OESOPHAGEAL DISEASE 5.PATIENTS WHO ARE PREGNANT

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of Intravenous Palonosetron versus Palonosetron with dexamethasone on the incidence of early & delayed postoperative nausea & vomiting during first 24hrs after induction of general anaesthesia in laparoscopic cholecystectomy surgeriesTimepoint: 1 hour , 2 hours, 3hours , 6 hours,24 hours—

Secondary

MeasureTime frame
1.To compare the severity of nausea & retching, need for rescue medications and to assess patient’s satisfaction. 2.To compare the incidence of any adverse effects between the two drugs Timepoint: 1 hour , 2 hours, 3hours , 6 hours,24 hours—

Countries

India

Contacts

Public ContactDr SHIVAKUMAR G

MANDYA INSTITUTE OF MEDICAL SCIENCES

dranashiv@gmail.com9900468451

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026