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To analyse the effectiveness of two different doses of nebulised dexmedetomidine in decreasing the hemodynamic response to laryngoscopy and endotracheal intubation

Efficacy of two different doses of nebulised dexmedetomidine on attenuation of stress response to laryngoscopy and endotracheal intubation- Double blinded randomised control trail - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/059506
Enrollment
60
Registered
2023-11-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intervention: Dexmedetomidine dose of 2mcg is nebulised for patient preoperatively .To find out the hemodynamic changes during intubation with increasing dose of dexmedetomidine Interve

Sponsors

Thamizhilakiya
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) patient Age between 18 and 60 years 2) ASA physical status 1 & 2 3) Normal airway belonging to both genders undergoing elective surgery under general anaesthesia with endotracheal intubation

Exclusion criteria

Exclusion criteria: 1) predicted difficult airway 2) pregnancy, renal failure, uncontrolled hypertension, seizure disorder 3) patient on antidepressant/antipsychotic drugs 4) patient with poor cardiopulmonary reserve 5)BMI >35Kkg/m2 6) Dexmedetomidine allergy

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of two different doses of nebulised dexmedetomidine in decreasing hemodynamic response to laryngoscopy & endotracheal intubationTimepoint: 30mins before induction to 2hrs postoperatively—

Secondary

MeasureTime frame
To observe the effect of postoperative nausea & vomiting & sorethroatTimepoint: 2hrs postoperatively—

Countries

India

Contacts

Public ContactThamizhilakiya

Sri Venkateshwara medical College hospital and research centre

dr.jayashridevi@gmail.com8754689690

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026