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Comparison of effectiveness and side effects of Brivaracetam and Levetiracetam in head injury patients

Comparison of effectiveness of Brivaracetam and Levetiracetam for prophylaxis of post traumatic seizures- A Randomised Control Study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/11/059371
Enrollment
100
Registered
2023-11-01
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G409- Epilepsy, unspecified

Interventions

Intervention1: Levetiracetam for traumatic brain injury: Comparison of effectiveness of brivaracetam and levetiracetam for prophylaxis of post traumatic seizures Tab 500 mg twice a day per oral for

Sponsors

Gmc neurosurgery dept goa
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with Traumatic brain injury with following findings will be included in the study Acute subdural hematoma Compound depressed fracture with underlying contusions Intracerebral hematoma Diffuse axonal injury Cerebral contusion Traumatic subarachnoid hemorrhage Patients with GCS equal and more than 5

Exclusion criteria

Exclusion criteria: Presence of Preexisting seizure disorder Presence of Other pathological brain condition known to cause seizures Patients with GCS less than 5

Design outcomes

Primary

MeasureTime frame
compare the efficacy and tolerability of LEV and BRV in patients with traumatic brain injury with risk of seizuresTimepoint: At one week of treatment—

Secondary

MeasureTime frame
Adverse effectsTimepoint: At 1 week 2week & 1 month—

Countries

India

Contacts

Public ContactPandya Rajan Bhalchandra

Goa medical college, Bambolim goa

Gmcslideshare@gmail.com8871702144

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026