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Evaluation of blood cell ratios in periodontitis patients with and without Type 2 Diabetes Mellitus Before and one month after scaling and root planing

Evaluation of Neutrophil to Lymphocyte (NLR),Platelet to lymphocyte (PLR) and Lymphocyte to Monocyte (LMR) ratios in peripheral blood of patients having periodontitis with type 2 diabetes mellitus before and one month after scaling and root planing - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/059333
Enrollment
63
Registered
2023-10-31
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Group 1- subject with periodontitis Group 2- subject with periodontitis with type 2 diabetes mellitus: measuring blood cell ratios at baseline and after one month of scaling and root pl

Sponsors

Dr. Nikita Vikasrao Palkar
Lead Sponsor
Dr Vishnudas Bhandari
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Group A 1.Subjects with clinically healthy periodontium, with no attachment loss and probing depth of less than or equal to 3 mm, 2.Group B: 1.Patients with Periodontitis stage II and stage III as per the 2017 American Academy of Periodontology Classification. 2.Patients with periodontitis stage II having clinical attachment loss of 3-4mm and maximum probing pocket depth =5 mm. 3.Patients with periodontitis stage III having clinical attachment loss of =5 mm and maximum probing pocket depth = 6mm.35 3.Group C: 1.Patients with periodontitis (stage II and stage III as per the 2017 American Academy of Periodontology classification) with diagnosed case of type 2 diabetes mellitus (Good diabetes control, HbA1c level 7%)

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Patient who has received periodontal treatment in last 6months. 3.Patient who is smoker or consuming any other form of tobacco. 4.Pregnant, lactating or postmenopausal women. 5.Hospitalized patients. 6.Subjects consuming antibiotic or other drugs in the past 6 months that affect their periodontal status. 7.History of any systemic disease which influences the values of NLR, PLR, and LMR ratio like any malignancy, cardiovascular diseases, rheumatic diseases, bipolar disorder, thyrotoxicosis, psoriasis other than type 2 diabetes mellitus for the test group (Group III) 8.History of any systemic disease for the control group. 9.If subject cannot maintain oral hygiene after non-surgical periodontal therapy (Gingival index score >1, plaque index >1).

Design outcomes

Primary

MeasureTime frame
changes in blood cell ratiosTimepoint: one month—

Secondary

MeasureTime frame
Plaque index ,gingival index, probing pocket depthTimepoint: one month—

Countries

India

Contacts

Public ContactDr Vishnudas Bhandari

Maharashtra Institute of Dental Sciences and Research Latur

nikkipalkar95@gmail.com9975256390

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026