Health Condition 1: Q209- Congenital malformation of cardiacchambers and connections, unspecified
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Department of Science and Technology
Kasturba Medical College
Eligibility
Inclusion criteria
Inclusion criteria: The study subjects will be pediatric live births and adult patients. The patients will be thoroughly screened for breathing problems, failure to thrive, heart murmur, fatigue, and family history by the cardiologist. Phenotypic data for the affected individuals and their family members will be obtained from the detailed clinical evaluation based on Electrocardiogram, Two-dimensional Echocardiography, cardiac catheterization and surgical findings. Peripheral blood samples from all the participants will be collected in EDTA K2 tubes after informed consent as per the extensive clinical criteria.
Exclusion criteria
Exclusion criteria: Patients with syndromic congenital heart defects will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genetic variants affect genotype-phenotype correlationTimepoint: 3 years | — |
Secondary
| Measure | Time frame |
|---|---|
| Genetic risk factors influence the disease severity.Timepoint: 2 years | — |
Countries
India
Contacts
Public ContactDr Tom Devasia
Kasturba Medical College
Outcome results
None listed