Study to compare effects of drug named nalbuphine and fentanyl when used together with drug bupivacaine in blocking brachial plexus nerve bundle through above the clavicle bone approach using ultrasound technique.

A COMPARATIVE STUDY TO EVALUATE THE EFFICACY OF NALBUPHINE VERSUS FENTANYL AS AN ADJUVANT TO 0.5% BUPIVACAINE IN ULTRASOUND GUIDED SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/059178

Enrollment

Registered

2023-10-27

Start date

Unknown

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S424- Fracture of lower end of humerus

Interventions

Intervention1: Inj Nalbuphine: 10mg along with 19ml 0.5% Bupivacaine for supraclavicular brachial plexus block. 24 hours observation Control Intervention1: Inj Fentanyl: 50mcg along with 19ml 0.5% Bup

Eligibility

Inclusion criteria

Inclusion criteria: Patients providing written informed consent voluntarily. 2) Patients belonging to age group 18 - 60 years of both sexes. 3) Patients measuring height 150-180cms and weighing 50-80kgs. 4) Patients scheduled for upper limb orthopedic surgery under supraclavicular brachial plexus block. 5) American society of anaesthesiologists (ASA) Grade I and II

Exclusion criteria

Exclusion criteria: 1) Patients refusing written informed consent. 2) Patients having infections at the site of injection. 3) Clinically significant coagulopathy. 4) Allergic to the study drugs. 5) Cardiogenic or hypovolemic shock. 6) Preexisting motor and sensory deficit. 7) Respiratory insufficiency.

Design outcomes

Primary

Measure	Time frame
1) Onset of sensory block 2) Onset of motor block 3) Duration of sensory block 4) Duration of motor block 5) Duration of postoperative analgesiaTimepoint: 24 hours	—

Secondary

Measure	Time frame
1)Heart Rate 2)Systolic BP 3)Diastolic BP 4)Mean BP 5)respiratory rate 6)saturation 7)Sedation score 8)VAS score 9)ComplicationsTimepoint: 24hours	—

Countries

India

Contacts

Public ContactDr MALATHI

Bangalore Medical College and Research Institute

kanthu.hirenallur@gmail.com9739006556

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026