A clinical study evaluating the antimicrobial effect of silver nanoparticle coated orthodontic bands on streptococcus mutans

Evaluation of Antimicrobial Effect of Silver Nanoparticle Coated Orthodontic Bands on Streptococcus mutans: A Split Mouth Randomized Controlled Study

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/10/059148

Enrollment

Registered

2023-10-26

Start date

Unknown

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K050- Acute gingivitis

Interventions

Intervention1: Silver nanoparticle coated orthodontic bands: Silver nanoparticle coating will be done on orthodontic bands and they will be evaluated for their antimicrobial activity against streptoco

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients coming to the department of orthodontics, undertaking orthodontic treatment 2)Patient giving consent for the study 3)Medical coating of silver nanoparticles on bands (carried out by PVD technique)

Exclusion criteria

Exclusion criteria: 1)Any other medical coating than silver nanoparticles 2)Patients with systemic disease 3)Patient taking any antibiotic medications 4)Patients with periodontal disease 5)Patients with active caries on the site of placement of band • Patients with age below 18 and above 35 years

Design outcomes

Primary

Measure	Time frame
Primary outcome is to evaluate the antimicrobial effectiveness of silver nanoparticle coated orthodontic bands on streptococcus mutans.The count of streptococcus mutans around the bands coated with silver nanoparticle after removing them a month after the placement will be recorded and will be compared to the count of streptococcus mutans around the uncoated bands.Timepoint: After the bands are placed in the mouth, 1 month after the placement, the bands both coated and uncoated will be removed and they will be assesed for antimicrobial activity against streptococcus mutans	—

Measure

Time frame

Primary outcome is to evaluate the antimicrobial effectiveness of silver nanoparticle coated orthodontic bands on streptococcus mutans.The count of streptococcus mutans around the bands coated with silver nanoparticle after removing them a month after the placement will be recorded and will be compared to the count of streptococcus mutans around the uncoated bands.Timepoint: After the bands are placed in the mouth, 1 month after the placement, the bands both coated and uncoated will be removed and they will be assesed for antimicrobial activity against streptococcus mutans

—

Secondary

Measure	Time frame
secondary outcome is to check the retention of silver nanoparticles on bandsTimepoint: it will be checked after 1 month of band placement	—

Countries

India

Contacts

Public ContactDr Ravindranath VK

MGM Dental College and Hospital, Navi Mumbai

tule.pragati@gmail.com9404740155

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026