Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Opioid free anaesthesia: General anaesthesia will be given to laparoscopic cholecystectomy patients without the use of opioids and the total duration of intervention will be 24 hours af
Sponsors
All India Institute of Medical Sciences Rishikesh
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients aged >18 years of all sexes, American society of anaesthesiology (ASA) grade I & II, undergoing laparoscopic cholecystectomy under general anaesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients refusing to consent for this study 2. Patients with chronic cardiovascular diseases (i.e., COPD, IHD, arrythmias etc.) 3. Patients with thoraco-lumbar spine pathology, unsuitable to epidural insertion. 4. Patients with allergy to local anaesthetics 5. Opioid dependent patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stress response to intubationTimepoint: change in heart rate from before to 1 minutes after intubation in 2 groups | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in systolic BPTimepoint: 1 minutes after intubation;Change in HR and BPTimepoint: 1 minutes after trocar insertion;Post operative pain (NRS score)Timepoint: immediate post op, 1 hr, 6 hr and 24 hr after extubation;Incidence of post-operative nausea and vomitingTimepoint: first 24 hrs after surgery;Patient satisfaction score-QoR 15 scoreTimepoint: on day 1 and on the day of discharge;Duration from surgery to mobilizationTimepoint: 2-3 days;Duration from surgery to dischargeTimepoint: Till discharge;incidence of complications like pruritus, constipationTimepoint: first 24 hours post op | — |
Countries
India
Contacts
Public ContactDeepak Singla
All India Institute of Medical Sciences, Rishikesh
Outcome results
None listed