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comparison of postoperative sore throat, hoarseness of voice and hemodynamic parameters by infation of intracuff by three groups air, saline and 2% alkalinised lignocaine.

A prospective randomized comparative study of intracuff inflation of air, saline and 2% alkalinised lignocaine on endotracheal tube induced tracheal morbidity after intubation. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/059137
Enrollment
138
Registered
2023-10-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K95- Diseases of the digestive system Health Condition 2: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 3: K598- Other specified functional intestinal disorders

Interventions

Intervention1: Air, Saline and 2% Alkalinised Lignocaine: Intracuff infation of 6ml of Air, 6ml of Saline and 6ml + 0.5 ml 2% Alkalinised Lignocaine during intubation to compare the incidence of post

Sponsors

vydehi institute of medical sciences and research centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA 1-2 2) Patients undergoing elective surgeries requiring general anaesthesia. 3) Patients who have given written informed consent.

Exclusion criteria

Exclusion criteria: Patients with history of allergy to local anaesthesia. Patients not willing to give consent. Tracheostomy Patient with laryngeal disease/surgery

Design outcomes

Primary

MeasureTime frame
To compare the incidence of post-extubation tracheal morbidity by using Saline, Air and 2% Lignocaine in form of: Sore throat Coughing Hoarseness in voice Timepoint: 1)Sore throat will be assessed in the recovery room by visual analong score ( VAS: 0-10) after extubation At 1st min, 5th min, 10th min, 1st hour and 24th hour. 2) Cough reflex will be noted and will be graded.—

Secondary

MeasureTime frame
To compare the endotracheal tube cuff pressure. To evaluate the haemodynamic changes during the intraoperative period. To compare difference in volume of agent injected & volume of agent aspirated at the end of procedure. Timepoint: 1. Endotracheal cuff pressure during inflation & deflation using manometer. 2. Cuff volume of injected agent during inflation & deflation. 3. Vitals ( Pulse rate, Blood pressure, Oxygen Saturation, End tidal carbon dioxide)—

Countries

India

Contacts

Public ContactDr Umamaheswar M

vydehi institute of medical sciences

ms@vimsmail.com9441249655

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026