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Comparison of effect of Intravenous Fentanyl vs Intravenous Dexmedetomidine on Characteristics of Spinal Anaesthesia

COMPARISON OF EFFECT OF IV FENTANYL VS IV DEXMEDETOMIDINE ON CHARACTERISTICS OF SPINAL ANAESTHESIA - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/10/059118
Enrollment
60
Registered
2023-10-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous Dexmedetomidine: Intravenous Injection Dexmedetomidine 0.5 mcg/kg (diluted to 10 ml with normal saline) over a period of 10 min as premedication 5 min before spinal anaesthe

Sponsors

Dr Runjhun Jain
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I or II fit patients. Ages between 18 and 65 years of either gender. Patients posted for infra umbilical surgery under sub-arachnoid block. Availability of informed consent

Exclusion criteria

Exclusion criteria: Patients with ASA physical status III or more. Patients with major neurological, cardiac, respiratory, metabolic, renal, hepatic disease or with coagulation abnormalities. Patients with contraindication for spinal anaesthesia. Patients with known allergies to the study drug. Patient refusal. Patients below 18 years and above 65 years of age

Design outcomes

Primary

MeasureTime frame
Time to achieve sensory blockade at T10, Time to achieve complete motor block, Highest level of sensory blockade achieved, Intraoperative hemodynamic parameters, Ramsay sedation score, Regression of spinal anaesthesia by two segmentsTimepoint: Basic vital parameters such as heart rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, oxygen saturation & Ramsay sedation score will be recorded. Then, these will be recorded after dural puncture & every 5 min for 15 min & then every 15 min interval till the end of surgery after spinal anaesthesia.

Secondary

MeasureTime frame
Time of requirement of the first dose of postoperative rescue analgesicTimepoint: 1 hour, 2 hour, 4 hour, 8 hour, 12 hour & 24 hour after administration of Sub Arachnoid Block

Countries

India

Contacts

Public ContactDr Runjhun Jain

Dr. D. Y. Patil Medical College Hospital & Research Centre

draparnabagle@gmail.com9422710943

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026