Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group A: Patients will be kept on NPO for 6 hours pre-operatively. One hour prior to being transferred to the operating rooms, intervention patients will be given oral tizanidine 4mg wi
Sponsors
All India Institute of Medical Sciences Patna
Eligibility
Inclusion criteria
Inclusion criteria: Patients planned for ORIF under general anesthesia for maxillofacial trauma will be included in the study. 1. Age between 18 and 65 years 2. ASA-PS Grade 1 & 2 3. BMI
Exclusion criteria
Exclusion criteria: 1. Patient refusal to participate in the study 2. Patients with known hypersensitivity to study medications. 3. Patients with renal or hepatic insufficiency 4. Patients on anti-hypertensive drugs, sedatives or alpha-2 agonists
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effect of tizanidine as a premedication on post-operative pain relief, as measured by the visual analog scale (VAS), in patients undergoing open reduction and internal fixation (ORIF) for maxillofacial trauma under general anesthesia.Timepoint: Postoperative period at 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| - To evaluate the requirement of rescue analgesic - To evaluate post-operative sedation - To monitor and evaluate haemodynamic parameters-heart rate (HR) and mean arterial pressure (MAP) - To assess incidence of PONVTimepoint: post-operative period at the intervals of 2, 6, 12 and 24 hours | — |
Countries
India
Contacts
Public ContactDr Kunal Singh
All India Institute of Medical Sciences Patna
Outcome results
None listed